What is the catalog number for EP2 receptor antagonist-3?

The catalog number for EP2 receptor antagonist-3 is T211961.

What sizes are available for EP2 receptor antagonist-3?

EP2 receptor antagonist-3 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EP2 receptor antagonist-3 come in?

EP2 receptor antagonist-3 is available in 2 different pack sizes.

Is EP2 receptor antagonist-3 in stock?

EP2 receptor antagonist-3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EP2 receptor antagonist-3?

EP2 receptor antagonist-3 is manufactured by Molfinity.

What is the estimated delivery time for EP2 receptor antagonist-3?

Estimated delivery time for EP2 receptor antagonist-3 is approximately 10 business day(s), depending on your location.

EP2 receptor antagonist-3

Product Specifications

CAS Number

1799626-16-6

Target

Prostaglandin Receptor, Beta Amyloid

Related Pathways

Immunology/Inflammation, Neuroscience, GPCR/G Protein

Bioactivity

EP2 receptor antagonist-3 is a selective antagonist of the EP2 receptor, with an IC50 of 8 nM determined in the hEP2 SPA assay and an IC50 of 50 nM in the hEP2 cAMP assay. It enhances macrophage-mediated clearance of Amyloid-β plaques. In CD-1 mice, it shows moderate clearance and good exposure, and exhibits good central nervous system (CNS) exposure in both mice and rats. EP2 receptor antagonist-3 is applicable for research in Alzheimer's disease.