P2X7 receptor antagonist-6
Product Specifications
CAS Number
1114621-31-6
Target
P2X Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
P2X7 receptorantagonist-6 (Compound 2g) is a negative allosteric antagonist of the P2X7 receptor, which shows an IC50 of 1.31 μM against hP2X7. This compound is applicable in the study of cancer, neurodegenerative diseases, inflammation, and infectious diseases.
Smiles
O=C(NC1=CC=C2OCOC2=C1)NC(CC3=CC=C(F)C=C3)CC4=CC=C(F)C=C4
Molecular Formula
C23H20F2N2O3
Molecular Weight
410.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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