VU6002703
Product Specifications
CAS Number
1934241-32-3
Target
AChR
Related Pathways
Neuroscience
Bioactivity
VU6002703 (Compound 17) is a brain-penetrant positive allosteric modulator (PAM) of the M4 muscarinic acetylcholine receptor (mAChR), exhibiting an EC50 of 0.6 ?M for hM4. This compound is useful for researching neuropsychiatric disorders and rare genetic central nervous system conditions.
Smiles
N=1C=NC(=C2C1SC(=C2C)C)N3CCC(OC4=CN=C(C=C4)C)CC3
Molecular Formula
C19H22N4OS
Molecular Weight
354.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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