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Refinicopan

Product Specifications

CAS Number

2922808-66-8

Target

Complement System

Related Pathways

Immunology/Inflammation

Bioactivity

Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM, demonstrating an inhibition activity on rabbit erythrocyte hemolysis with an IC50 of 41 nM. It possesses excellent pharmacokinetic and pharmacodynamic properties.

Smiles

O=C(O)CC=1C=CC=CC1OCC2=CC(=CC(=C2)N3CCC4(CC3)CC4)C=5C=CC=C(C5)CN

Molecular Formula

C29H32N2O3

Molecular Weight

456.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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