Refinicopan
Product Specifications
CAS Number
2922808-66-8
Target
Complement System
Related Pathways
Immunology/Inflammation
Bioactivity
Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM, demonstrating an inhibition activity on rabbit erythrocyte hemolysis with an IC50 of 41 nM. It possesses excellent pharmacokinetic and pharmacodynamic properties.
Smiles
O=C(O)CC=1C=CC=CC1OCC2=CC(=CC(=C2)N3CCC4(CC3)CC4)C=5C=CC=C(C5)CN
Molecular Formula
C29H32N2O3
Molecular Weight
456.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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