Quecitinib
Product Specifications
CAS Number
2416858-84-7
Target
JAK, Cytochromes P450
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Chromatin/Epigenetic, JAK/STAT signaling, Stem Cells, Metabolism
Bioactivity
Quecitinib (QY201) is an orally active dual inhibitor of JAK1/TYK2. It acts as a substrate for cytochrome P450 3A, predominantly metabolized into mono-oxidized and glucuronidated products. Quecitinib demonstrates favorable pharmacokinetic properties and safety. It is applicable for research on atopic dermatitis and other autoimmune diseases.
Smiles
[C@H](C)(O)C=1N(C2=C3C(NC=C2N1)=NC=C3)N4CCC(CC#N)CC4
Molecular Formula
C17H20N6O
Molecular Weight
324.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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