PSMA-DIM

PSMA-DIM is a dimeric PSMA ligand with a Kd value of 37.09 nM for LNCaP cells. It can be radiolabeled with [68Ga]Ga to form [68Ga]Ga-PSMA-DIM, which effectively differentiates cells and animal models with varying PSMA expression levels. [68Ga]Ga-PSMA-DIM exhibits high uptake in LNCaP cells and maximizes tumor uptake. PSMA-DIM is applicable in prostate cancer (PCa) research.