What is the catalog number for MAPK-IN-5?

The catalog number for MAPK-IN-5 is T211815.

What sizes are available for MAPK-IN-5?

MAPK-IN-5 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does MAPK-IN-5 come in?

MAPK-IN-5 is available in 2 different pack sizes.

Is MAPK-IN-5 in stock?

MAPK-IN-5 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MAPK-IN-5?

MAPK-IN-5 is manufactured by Molfinity.

What is the estimated delivery time for MAPK-IN-5?

Estimated delivery time for MAPK-IN-5 is approximately 10 business day(s), depending on your location.

MAPK-IN-5

Product Specifications

CAS Number

2579683-39-7

Target

ROS, p38 MAPK, Caspase, PARP, Bcl-2 Family, Apoptosis

Related Pathways

DNA Damage/DNA Repair, Proteases/Proteasome, Apoptosis, Immunology/Inflammation, Chromatin/Epigenetic, MAPK

Bioactivity

MAPK-IN-5 is a potent inhibitor of MAPK, with an IC50 value of 1.35 μM in HeLa cells. It induces ROS-mediated DNA damage and mitochondrial apoptosis (apoptosis) via the MAPK pathway. MAPK-IN-5 significantly inhibits colony formation in HeLa cells, reduces viable cell numbers, suppresses cell migration, and arrests the cell cycle at the G2/M phase. It is applicable in cervical cancer research.