GCN2 activator-1
Product Specifications
Target
PERK
Related Pathways
Apoptosis
Bioactivity
GCN2 activator-1 (Compound 20) is a GCN2 activator that binds to the ATP pocket of GCN2 and activates it in a GCN1-independent manner. It can stimulate the integrated stress response (ISR) in cells and inhibits PKR with an IC50 of 3.75 µM. GCN2 activator-1 is utilized for research on pulmonary veno-occlusive disease (PVOD) .
Smiles
N=1C=CC=NC1NC2=NC(=CS2)C=3SC(=NC3C)N
Molecular Formula
C11H10N6S2
Molecular Weight
290.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/390881274074021969/T211805
CAS Number
315705-10-3
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1196543-01 0.02 mg (E-Coli)
Recombinant Variola virus Protein C6 (B16L, C6L, D12L, D9L)
Ask
View Details 
MBS1196543-02 0.1 mg (E-Coli)
Recombinant Variola virus Protein C6 (B16L, C6L, D12L, D9L)
Ask
View Details MBS1196543-03 0.02 mg (Yeast)
Recombinant Variola virus Protein C6 (B16L, C6L, D12L, D9L)
Ask
View Details MBS1196543-04 0.1 mg (Yeast)
Recombinant Variola virus Protein C6 (B16L, C6L, D12L, D9L)
Ask
View Details MBS1196543-05 0.02 mg (Baculovirus)
Recombinant Variola virus Protein C6 (B16L, C6L, D12L, D9L)
Ask
View Details MBS1196543-06 0.02 mg (Mammalian-Cell)
Recombinant Variola virus Protein C6 (B16L, C6L, D12L, D9L)
Ask
View Details