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MST3-IN-1

Product Specifications

Target

Caspase|||Bcl-2 Family|||Hippo pathway|||Apoptosis

Related Pathways

Apoptosis|||Stem Cells|||Proteases/Proteasome

Bioactivity

MST3-IN-1 is a selective and orally active MST3 inhibitor with an IC50 of 122.4 nM. It exhibits antiproliferative activity in HepG2 cells, effectively induces apoptosis, and causes cell cycle arrest at the G2/M phase. In HepG2 xenograft mouse models, MST3-IN-1 significantly suppresses tumor growth, making it useful for liver cancer research.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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