MST3-IN-1
Product Specifications
Target
Caspase|||Bcl-2 Family|||Hippo pathway|||Apoptosis
Related Pathways
Apoptosis|||Stem Cells|||Proteases/Proteasome
Bioactivity
MST3-IN-1 is a selective and orally active MST3 inhibitor with an IC50 of 122.4 nM. It exhibits antiproliferative activity in HepG2 cells, effectively induces apoptosis, and causes cell cycle arrest at the G2/M phase. In HepG2 xenograft mouse models, MST3-IN-1 significantly suppresses tumor growth, making it useful for liver cancer research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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