GRL-07524
Product Specifications
Target
HIV Protease
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Bioactivity
GRL-07524 (Compound 4e) is a potent HIV-1 protease inhibitor with a Ki of 0.22 nM. It contains an oxaspirocarbamate as the P2 ligand and demonstrates strong antiviral activity, with an EC50 of 210 nM. GRL-07524 can bind to the active site of HIV-1PR and crucial catalytic residues, interacting with one of four symmetric-independent molecules.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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