PRMT5-MTA-IN-6
Product Specifications
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
PRMT5-MTA-IN-6 (Compound 31) is a selective inhibitor of PRMT5 in conjunction with MTA, exhibiting potent inhibitory activity against PRMT5?MTA with an IC50 of 6.6 nM. It selectively inhibits the growth of MTAP-deficient HCT-116 cells with an IC50 of 319 nM and is useful for studying MTAP-deficient tumors.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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