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PRMT5-MTA-IN-6

Product Specifications

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Bioactivity

PRMT5-MTA-IN-6 (Compound 31) is a selective inhibitor of PRMT5 in conjunction with MTA, exhibiting potent inhibitory activity against PRMT5?MTA with an IC50 of 6.6 nM. It selectively inhibits the growth of MTAP-deficient HCT-116 cells with an IC50 of 319 nM and is useful for studying MTAP-deficient tumors.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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