PFI-7-O-C4-piperazin
Product Specifications
Target
E3 Ligase Ligand-Linker Conjugate
Related Pathways
PROTAC
Bioactivity
PFI-7-O-C4-piperazin is an E3 ligase ligand-linker conjugate used in the synthesis of PROTACs, such as NEP162. The E3 ligase ligand of NEP162 (PFI-7) is a highly selective GID4 antagonist (KD= 0.22 ?M) . NEP162 is a potent and highly selective BRD4 PROTAC degrader with antitumor activity.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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