Forvisirvat
Product Specifications
CAS Number
2135638-06-9
Target
Sirtuin
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
Forvisirvat (SP-624) is an orally active, brain-permeable, and selective activator of the silent information regulator protein 6 (SIRT6) . It enhances the deacetylase activity of SIRT6, promotes DNA repair and mitochondrial health, and demonstrates antidepressant effects in animal models. Forvisirvat holds promise for the investigation of major depressive disorder.
Smiles
O=C1[C@@]2(OC=3C1=C(OC)C=C(C3Cl)C=4OC(C)=NN4)C(OC)=CC(=O)C[C@H]2C
Molecular Formula
C19H17ClN2O6
Molecular Weight
404.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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