DPC 684
Product Specifications
CAS Number
284661-73-0
Target
HIV Protease
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Bioactivity
DPC 684 is a potent and selective HIV-1 protease inhibitor with an IC90 of 5.7-40 nM and a Ki of 0.021 nM. It competitively inhibits HIV-1 protease, preventing viral polyprotein cleavage. Compared to cellular proteases, DPC 684 shows high selectivity for retroviral proteases. The compound exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant HIV-1 proteases, with an IC90 of 1.9-6.3 nM. DPC 684 is significant for HIV research.
Smiles
[C@@H]([C@@H](CN(S(=O)(=O)C1=CC=C(N)C=C1)CC(C)C)O)(CC2=CC=CC=C2)NC([C@@H](NC(CNCC3=CC(F)=CC=C3)=O)[C@](C)(C)C)=O
Molecular Formula
C35H48FN5O5S
Molecular Weight
669.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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