Lorotomidate
Product Specifications
CAS Number
2093287-60-4
Target
GABA Receptor
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
Lorotomidate (Example 16) is a GABAA receptor agonist with anesthetic properties, demonstrated by an ED50 of 2 mg/kg and an LD50 of 46.5 mg/kg in Kunming mice via intravenous injection. Lorotomidate does not inhibit corticosteroid secretion in animals, indicating a favorable safety profile.
Smiles
[C@H](C)(N1C(C(OCC)=O)=C(F)N=C1)C2=CC=CC=C2
Molecular Formula
C14H15FN2O2
Molecular Weight
262.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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