Arrestin-3 modulator-1
Product Specifications
CAS Number
1386112-75-9
Target
Arrestin, Adrenergic Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
Arrestin-3 modulator-1 (Compound LSH-3) is a regulator of Arrestin-3. It binds with Arrestin-3 at the inter-domain interface. This compound enhances the recruitment of Arrestin-3 to phosphorylated-deficient β2AR in cells and elevates FRET levels. Arrestin-3 modulator-1 is applicable in studies related to congenital diseases such as retinal degeneration, hyperthyroidism, and obesity.
Smiles
O=C(NC1=CC=CC(=C1)NC(=O)C2CC2)C3=CC(SC)=CC=C3Cl
Molecular Formula
C18H17ClN2O2S
Molecular Weight
360.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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