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Arrestin-3 modulator-1

Product Specifications

CAS Number

1386112-75-9

Target

Arrestin, Adrenergic Receptor

Related Pathways

Neuroscience, GPCR/G Protein

Bioactivity

Arrestin-3 modulator-1 (Compound LSH-3) is a regulator of Arrestin-3. It binds with Arrestin-3 at the inter-domain interface. This compound enhances the recruitment of Arrestin-3 to phosphorylated-deficient β2AR in cells and elevates FRET levels. Arrestin-3 modulator-1 is applicable in studies related to congenital diseases such as retinal degeneration, hyperthyroidism, and obesity.

Smiles

O=C(NC1=CC=CC(=C1)NC(=O)C2CC2)C3=CC(SC)=CC=C3Cl

Molecular Formula

C18H17ClN2O2S

Molecular Weight

360.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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