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Anticancer agent 276

Product Specifications

Target

VEGFR|||Estrogen Receptor/ERR|||c-Met/HGFR|||EGFR|||Topoisomerase

Related Pathways

JAK/STAT signaling|||Angiogenesis|||DNA Damage/DNA Repair|||Tyrosine Kinase/Adaptors|||Endocrinology/Hormones

Bioactivity

Anticanceragent 276 (Compound 5) is a multitarget anticancer compound. It exhibits potent antitumor activity against human cancer cells, with IC50 values of 6.90 ?M for HEPG2 cells and 4.48 ?M for MCF7 cells. Anticanceragent 276 interacts strongly and stably with multiple targets, including topoisomerase II, VEGFR2, c-Met, EGFR, and ER?.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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