What is the catalog number for MRC-G-001?

The catalog number for MRC-G-001 is T211674.

What sizes are available for MRC-G-001?

MRC-G-001 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does MRC-G-001 come in?

MRC-G-001 is available in 2 different pack sizes.

Is MRC-G-001 in stock?

MRC-G-001 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MRC-G-001?

MRC-G-001 is manufactured by Molfinity.

What is the estimated delivery time for MRC-G-001?

Estimated delivery time for MRC-G-001 is approximately 10 business day(s), depending on your location.

MRC-G-001

Product Specifications

Target

Apoptosis, JAK, EGFR, STAT

Related Pathways

Apoptosis, Stem Cells, Angiogenesis, JAK/STAT signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors

Bioactivity

MRC-G-001 is a Genipin derivative with an IC50 value of 117 μM against A549 cancer cells. It inhibits the phosphorylation of EGFR, JAK1, and STAT3, and modulates the expression of proteins related to epithelial-mesenchymal transition (EMT), thereby suppressing cell migration and invasion. MRC-G-001 induces cell cycle arrest and apoptosis (apoptosis) and is applicable in studies of cancers, including non-small cell lung cancer.