IDO1/TDO-IN-9
Product Specifications
CAS Number
1878200-88-4
Target
Indoleamine 2,3-Dioxygenase (IDO), IDO
Related Pathways
Metabolism
Bioactivity
IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO), with an IC50 value of less than 1 μM. It effectively inhibits the activity of IDO1 and TDO, preventing the degradation of tryptophan into kynurenine, thereby restoring immune activity in the tumor microenvironment and inhibiting tumor growth. IDO1/TDO-IN-9 shows potential for cancer research.
Smiles
FC1=CC2=C(N=C1Cl)ON=C2N
Molecular Formula
C6H3ClFN3O
Molecular Weight
187.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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