STAT3-IN-44
Product Specifications
Target
Apoptosis, Caspase, Bcl-2 Family, STAT
Related Pathways
Apoptosis, Stem Cells, Proteases/Proteasome, JAK/STAT signaling
Bioactivity
STAT3-IN-44 is a potent STAT3 inhibitor with IC50 values of 1.84 μM (C6 cells) and 4.81 μM (A549 cells) . It inhibits the phosphorylation of STAT3, downregulates Bcl-2 expression, and upregulates Caspase-3 expression, thereby promoting late-stage apoptosis. STAT3-IN-44 effectively suppresses tumor cell proliferation and migration and is applicable in research on cancers such as glioma and lung cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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