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PIM1-IN-8

Product Specifications

Target

Interleukin, NF-κB, Pim

Related Pathways

NF-κB, JAK/STAT signaling, Immunology/Inflammation, Chromatin/Epigenetic

Bioactivity

PIM1-IN-8 is an inhibitor targeting the PIM1/p65 signaling pathway. It suppresses the expression of α-SMA and type I collagen in activated fibroblasts and inhibits TGF-β-induced migration. In a Bleomycin (BLM) -induced pulmonary fibrosis mouse model, PIM1-IN-8 alleviates lung fibrosis. This compound can be utilized in research on idiopathic pulmonary fibrosis (IPF) .

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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