CCL-34
Product Specifications
CAS Number
943316-60-7
Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
CCL-34 is an activator of Toll-like receptor 4 (TLR4) . It significantly induces the expression of CD83 on dendritic cells (DC) and the production of IL-12p70 in a dose-dependent manner, thereby promoting DC maturation. CCL-34 enhances the allostimulatory activity of DC on the proliferation of naive CD4+CD45+RA+ T cells and their secretion of IFN-?. Furthermore, CCL-34 can enhance antigen presentation capability in mice inoculated with doxorubicin-treated colorectal cancer cells. CCL-34 is applicable for research in immune stimulation.
Smiles
O(C[C@@H](C(NCCCCCCCCCCC)=O)NC(CCCCCCCCCCC)=O)[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
Molecular Formula
C32H62N2O8
Molecular Weight
602.84
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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