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PROTAC FLT3/GSPT1/IKZF1/3 degrader-1

Product Specifications

Target

PROTACs, FLT, Molecular Glues, IKZF

Related Pathways

PROTAC, Tyrosine Kinase/Adaptors, Immunology/Inflammation, Angiogenesis

Bioactivity

PROTACFLT3/GSPT1/IKZF1/3 degrader-1 is an FLT3 PROTAC degrader with DC50 = 1.2 nM. It functions as a molecular glue to degrade its brain substrates and exhibits antiproliferative activity against resistant acute myeloid leukemia (AML) cells, showing potential applications in AML research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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