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VEGFR-2-IN-71

Product Specifications

Target

Microtubule Associated, Apoptosis, VEGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis, Cytoskeletal Signaling

Bioactivity

VEGFR-2-IN-71 is a dual inhibitor of VEGFR2/tubulin. It suppresses tumor cell proliferation, induces apoptosis and cell cycle arrest, and inhibits angiogenesis in the chicken embryo chorioallantoic membrane (CAM) model. By targeting VEGFR2 and tubulin, VEGFR-2-IN-71 hinders tumor growth in the HGC-27 xenograft model. It exhibits low oral bioavailability in rats and is applicable in cancer research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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