PDIC-NN dimethanesulfonate
Product Specifications
CAS Number
3040919-39-6
Target
STING, ROS, Apoptosis
Related Pathways
Apoptosis, Immunology/Inflammation
Bioactivity
PDIC-NN dimethanesulfonate (PDIC-NS) is a STING activator with anticancer properties. It increases the levels and stability of endogenous cyclic dinucleotides (CDN) . PDIC-NN dimethanesulfonate triggers a burst of reactive oxygen species (ROS) and causes significant mitochondrial damage. It induces apoptosis and inhibits DNA replication. Additionally, it activates the cGAS-STING signaling pathway, enhancing the immunogenicity of tumor cells and triggering a strong innate immune response.
Smiles
O=C1C2=CC(Cl)=C3C4=C(Cl)C=C5C(=O)N(C(=O)C6=CC(Cl)=C(C=7C(Cl)=CC(C(=O)N1CCN(C)C)=C2C37)C4=C56)CCN(C)C.O=S(=O)(O)C
Molecular Formula
C33H28Cl4N4O7S
Molecular Weight
766.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC042494-100 1x 100 µL
FOLH1 / PSMA (Prostate Epithelial Marker) (FOLH1/2494), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
HA610142 100 µg
Lambda Light Chain Recombinant Mouse monoclonal Antibody
Sign In for Pricing
View Details 