3′-Azido-2′,3′-dideoxy-GTP
Product Specifications
CAS Number
94059-38-8
Target
Telomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
3′-Azido-2′,3′-dideoxy-GTP (AZddGTP) is a selective telomerase inhibitor with a Ki of 1.5 μM. This compound can be integrated by telomerase into the 3′ end of DNA and has the ability to inhibit telomerase activity in HeLa cells in vitro.
Smiles
O=C1C2=C(N(C=N2)[C@@H]3O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](N=[N+]=[N-])C3)NC(N)=N1
Molecular Formula
C10H15N8O12P3
Molecular Weight
532.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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