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3′-Azido-2′,3′-dideoxy-GTP

Product Specifications

CAS Number

94059-38-8

Target

Telomerase

Related Pathways

DNA Damage/DNA Repair

Bioactivity

3′-Azido-2′,3′-dideoxy-GTP (AZddGTP) is a selective telomerase inhibitor with a Ki of 1.5 μM. This compound can be integrated by telomerase into the 3′ end of DNA and has the ability to inhibit telomerase activity in HeLa cells in vitro.

Smiles

O=C1C2=C(N(C=N2)[C@@H]3O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](N=[N+]=[N-])C3)NC(N)=N1

Molecular Formula

C10H15N8O12P3

Molecular Weight

532.19

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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