15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
Product Specifications
CAS Number
1947405-90-4
Target
Others, PPAR, Endogenous Metabolite
Related Pathways
Others, Metabolism, DNA Damage/DNA Repair
Bioactivity
15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivative of 15-Deoxy-Δ-12,14-prostaglandin J2. The 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. This compound acts as a selective PPARγ (with an EC50 of 2 μM) and covalent PPARδ agonist. Additionally, 15-Deoxy-Δ-12,14-prostaglandin J2 effectively promotes the differentiation of C3H10T1/2 fibroblasts into adipocytes, with an EC50 of 7 μM.
Smiles
C(\C=C\CCCCC)=C/1\[C@@H](C/C=C\CCCC(OC(CO)CO)=O)C=CC1=O
Molecular Formula
C23H34O5
Molecular Weight
390.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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