SGC0946 TFA
Product Specifications
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
SGC0946 TFA is a selective inhibitor of DOT1L with an IC50 value of 0.3 nM. It induces G1 phase arrest in cancer cells by inhibiting DOT1L and reduces cellular self-renewal and metastatic potential while promoting cell differentiation. SGC0946 TFA is applicable in research for tumors such as leukemia and breast cancer and serves as a probe for studying the cellular mechanisms of DOT1L in both normal and diseased cells.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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