PZ671
Product Specifications
Target
PROTACs, Apoptosis, Bcl-2 Family
Related Pathways
Apoptosis, PROTAC
Bioactivity
PZ671 is a potent PROTAC degrader targeting Bcl-xL, exhibiting an IC50 of 1.3 nM in MOLT-4 cells and a DC50 of 0.9 nM for Bcl-xL. It induces apoptosis in MOLT-4 cells and effectively inhibits tumor growth in MOLT-4 xenograft mice, while quickly restoring transiently reduced platelet counts. PZ671 is applicable in cancer research, including studies on small cell lung cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6478851-01 0.1 mL
Granulocyte Colony Stimulating Factor (G-CSF) (HRP)
Sign In for Pricing
View Details MBS6478851-02 5x 0.1 mL
Granulocyte Colony Stimulating Factor (G-CSF) (HRP)
Sign In for Pricing
View Details 
TRV-0036041-01 20 µL
Polyclonal Antibody to Cluster Of Differentiation 83 (CD83)
Sign In for Pricing
View Details TRV-0036041-02 100 µL
Polyclonal Antibody to Cluster Of Differentiation 83 (CD83)
Sign In for Pricing
View Details TRV-0036041-03 200 µL
Polyclonal Antibody to Cluster Of Differentiation 83 (CD83)
Sign In for Pricing
View Details TRV-0036041-04 1 mL
Polyclonal Antibody to Cluster Of Differentiation 83 (CD83)
Sign In for Pricing
View Details