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VEGFR-2-IN-70

Product Specifications

Target

MDM-2/p53, Apoptosis, Bcl-2 Family, VEGFR, Caspase

Related Pathways

Proteases/Proteasome, Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis

Bioactivity

VEGFR-2-IN-70 is a potent VEGFR-2 inhibitor with an IC50 of 18.04 nM. It exhibits cytotoxicity against A549 and MCF-7 cancer cells, with IC50 values of 0.43 μM and 3.8 μM, respectively. The compound induces G1 phase cell cycle arrest and apoptosis (apoptosis) in lung cancer cells. VEGFR-2-IN-70 is applicable in cancer research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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