Taligantinib
Product Specifications
CAS Number
2243235-80-3
Target
VEGFR, c-Met/HGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
Taligantinib (Compound Example 70) is an orally active and selective dual inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR-2) and hepatocyte growth factor receptor (c-Met) . It effectively suppresses tumor angiogenesis and cell proliferation, and holds potential for the study of solid tumors such as non-small cell lung cancer and hepatocellular carcinoma.
Smiles
O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC4=CC=NC5=CC(OCCCN6CCOCC6)=C7OCCOC7=C54)C(F)=C3)CC2
Molecular Formula
C35H34F2N4O7
Molecular Weight
660.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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