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NADH-IN-3

Product Specifications

Target

Endogenous Metabolite

Related Pathways

Metabolism

Bioactivity

NADH-IN-3 (Compound C4-1) is an NADH inhibitor with a minimum inhibitory concentration (MIC) of 4 ?g/mL (13.042 ?M) against the type II NADH dehydrogenase of Mycobacterium tuberculosis (Mtb) . It effectively blocks ATP synthesis and demonstrates potent inhibitory effects on both single-drug (Rifampicin and Isoniazid) and multidrug-resistant (Mtb) strains, exhibiting antibacterial activity while maintaining low cytotoxicity towards HepG2 cells (SI: 16.52) .

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/390881968868868268/T211509

Available Sizes

Curated Selection

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