NADH-IN-3
Product Specifications
Target
Endogenous Metabolite
Related Pathways
Metabolism
Bioactivity
NADH-IN-3 (Compound C4-1) is an NADH inhibitor with a minimum inhibitory concentration (MIC) of 4 ?g/mL (13.042 ?M) against the type II NADH dehydrogenase of Mycobacterium tuberculosis (Mtb) . It effectively blocks ATP synthesis and demonstrates potent inhibitory effects on both single-drug (Rifampicin and Isoniazid) and multidrug-resistant (Mtb) strains, exhibiting antibacterial activity while maintaining low cytotoxicity towards HepG2 cells (SI: 16.52) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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