LO-3-63
Product Specifications
Target
E1/E2/E3 Enzyme, CDK
Related Pathways
Ubiquitination, Cell Cycle/Checkpoint
Bioactivity
LO-3-63 is a Ribociclib analogue featuring a truncated fumaramide group and acts as a CDK4/6 degrader with PROTAC properties. It degrades CDK4/6 in cells via a CUL4DCAF16-dependent pathway.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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