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LO-3-63

Product Specifications

Target

E1/E2/E3 Enzyme, CDK

Related Pathways

Ubiquitination, Cell Cycle/Checkpoint

Bioactivity

LO-3-63 is a Ribociclib analogue featuring a truncated fumaramide group and acts as a CDK4/6 degrader with PROTAC properties. It degrades CDK4/6 in cells via a CUL4DCAF16-dependent pathway.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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