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Auristatin S

Product Specifications

CAS Number

3028453-70-2

Target

Others|||Microtubule Associated

Related Pathways

Cytoskeletal Signaling|||Others

Bioactivity

AuristatinS is a potent anti-tumor agent that serves as an Auristatin payload. It effectively reduces the bystander effect and decreases off-target toxicity. In the Karpas/KarpasBVR cell model, AuristatinS exhibits excellent tolerability. It can be used as the cytotoxic component in antibody-drug conjugates (ADCs) for treating various types of cancer.

Smiles

[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)CO)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C)C)CO)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]

Molecular Formula

C38H65N5O8

Molecular Weight

719.95

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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