Lepetegravir

2808219-64-7

HIV Protease

Microbiology/Virology, Proteases/Proteasome

Lepetegravir (Example 24) is an inhibitor of HIV integrase, demonstrating antiviral activity with an EC50 of 0.98 nM in MT-4 cells.

O=C1C=2N([N@@]3CN1[C@@H](C)C=C[C@H]3C)C=C(C(NCC4=C(F)C=C(F)C=C4F)=O)C(=O)C2O

C21H19F3N4O4

448.4

Ice Packs

-20°C