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KPC-2-IN-3

Product Specifications

Target

Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with an IC50 of 0.533 ?M and a Ki of 0.194 ?M. It works synergistically with Meropenem to exhibit antibacterial activity against carbapenem-resistant K. pneumoniae K47-25, reducing bacterial count and demonstrating a post-antibiotic effect. Additionally, KPC-2-IN-3 significantly decreases lung bacterial load in a mouse pneumonia model.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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