ALG-001075
Product Specifications
CAS Number
2495324-66-6
Target
HBV
Related Pathways
Microbiology/Virology
Bioactivity
ALG-001075, a capsid assembly modulator (CAM), is an orally active inhibitor of HBV. It effectively suppresses HBV DNA production in primary human hepatocytes and significantly reduces extracellular levels of HBsAg/HBeAg and intracellular HBV RNA. In AAV-HBV mouse models, ALG-001075 notably decreases HBV DNA levels. It can be utilized in research related to chronic hepatitis B (CHB) .
Smiles
N#CC1=CC(=CC=C1F)NC(=O)C2=C(C(C(=O)C(=O)NC3(C#C)COC3)=C(N2C)C)C
Molecular Formula
C22H19FN4O4
Molecular Weight
422.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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