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ALG-001075

Product Specifications

CAS Number

2495324-66-6

Target

HBV

Related Pathways

Microbiology/Virology

Bioactivity

ALG-001075, a capsid assembly modulator (CAM), is an orally active inhibitor of HBV. It effectively suppresses HBV DNA production in primary human hepatocytes and significantly reduces extracellular levels of HBsAg/HBeAg and intracellular HBV RNA. In AAV-HBV mouse models, ALG-001075 notably decreases HBV DNA levels. It can be utilized in research related to chronic hepatitis B (CHB) .

Smiles

N#CC1=CC(=CC=C1F)NC(=O)C2=C(C(C(=O)C(=O)NC3(C#C)COC3)=C(N2C)C)C

Molecular Formula

C22H19FN4O4

Molecular Weight

422.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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