What is the catalog number for IDO1-IN-27?

The catalog number for IDO1-IN-27 is T211421.

What sizes are available for IDO1-IN-27?

IDO1-IN-27 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does IDO1-IN-27 come in?

IDO1-IN-27 is available in 2 different pack sizes.

Is IDO1-IN-27 in stock?

IDO1-IN-27 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IDO1-IN-27?

IDO1-IN-27 is manufactured by Molfinity.

What is the estimated delivery time for IDO1-IN-27?

Estimated delivery time for IDO1-IN-27 is approximately 10 business day(s), depending on your location.

IDO1-IN-27

Product Specifications

Target

TNF, Interleukin, Indoleamine 2,3-Dioxygenase (IDO)

Related Pathways

Immunology/Inflammation, Apoptosis, Metabolism

Bioactivity

IDO1-IN-27 (Compound I-1) is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), displaying an IC50 of 0.3951 μM against recombinant hIDO1. It also inhibits hIDO1 expression in HeLa cells with an EC50 of 62 nM. By reducing the mRNA expression of pro-inflammatory factors (TNF-α, IL-6, and IL-1β), IDO1-IN-27 effectively stimulates T cell proliferation and simultaneously inhibits the growth of LLC cells.