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DiABZI-a1

Product Specifications

CAS Number

2138299-43-9

Target

STING

Related Pathways

Immunology/Inflammation

Bioactivity

DiABZI-a1 is an orthogonal STING agonist with an EC50 of 117 nM for inducing IFNβ in human PBMCs. This compound is applicable in the study of monogenic autoinflammatory diseases such as SAVI disease.

Smiles

C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CC2OC)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OC

Molecular Formula

C36H40N12O6

Molecular Weight

736.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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