Rf470 TFA
Product Specifications
CAS Number
2369899-34-1
Target
Others, Antibacterial
Related Pathways
Microbiology/Virology, Others
Bioactivity
Rf470 (Rotor NO.4) TFA is an FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently integrated into bacterial peptidoglycan. In its free state, Rf470 TFA exhibits weak fluorescence, which significantly increases upon integration into peptidoglycan by transpeptidase catalysis. This fluorescence change allows Rf470 TFA to be used for real-time monitoring of peptidoglycan biosynthesis, detecting transpeptidase activity, and screening antibiotics.
Smiles
C(C(O)=O)(F)(F)F.C(CC(NCCCC[C@H](C(O)=O)N)=O)N1C=2C(=CC(=CC2)C=3SC(/C=C(/C(O)=O)\C#N)=CC3)CCC1
Molecular Formula
C28H31F3N4O7S
Molecular Weight
624.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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