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(E) -JP-2-196 TFA

Product Specifications

CAS Number

3065021-33-9

Target

E3 Ligase Ligand-Linker Conjugate

Related Pathways

PROTAC

Bioactivity

JP-2-196 (TFA) is a molecular glue handle that binds in vitro with E3 ubiquitin ligases [RNF126, LRSAM1, RNF40, MID2, and RNF14]. It is applicable in the synthesis of molecular glue degraders.

Smiles

C(C(O)=O)(F)(F)F.C(/C=C/C(=O)N1CCNCC1)(=O)C2=CC=C(OC)C=C2

Molecular Formula

C17H19F3N2O5

Molecular Weight

388.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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