YTHu78
Product Specifications
Target
Histone Demethylase, Caspase, PARP, Apoptosis, PROTACs
Related Pathways
Proteases/Proteasome, Chromatin/Epigenetic, PROTAC, DNA Damage/DNA Repair, Apoptosis
Bioactivity
YTHu78 is a KDM5B PROTAC-based degrader. It induces the degradation of KDM5B through the ubiquitin-proteasome system and triggers apoptosis in MV-4-11 and MM.1S cell lines. YTHu78 demonstrates significant antiproliferative activity against various hematologic tumor cell lines and is useful for studying hematological malignancies.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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